Metabolics Report

The Metabolics Report transforms our understanding of how genes confer metabolic individuality and underpin energy regulation, longevity and healthspan. 

Metabolism refers to all cellular chemical reactions and is essential for life. It involves many interconnected pathways that can be divided into ‘anabolism’ (‘build up’ e.g synthesis of sugars, fats, proteins and nucleic acids) and catabolism (‘break down’ e.g., releasing energy in the form of ATP). These complex processes, and the balance between them, are the key to energy metabolism and healthy cell structure and function. 

The comprehensive Metabolics report presents the genes that can powerfully influence key pathways driving human metabolism. It incorporates over 40 genes and 50 SNPs across 6 pathways, including appetite regulation, nutrient sensing, sugar and fat metabolism, cholesterol and bile, mitochondria and inflammation.

Genes Included

Appetite Regulation: BDNF, FAAH, FTO, LEPR, MC4R, NPY, POMC
Nutrient Sensing: ADIPOQ, FOXO3, HIF1A, IRS1, PARP1, PGC1A, PPARA, PPARG, SIRT1, VEGFA
Sugar Metabolism: AMPD1, GCK, GLUT2, IRS1, PPARG, TCF7L2
Fat Metabolism: ADRB3, CD36, CPT1A, FABP2, LPL, PLIN1, PPARA, SREBF1
Cholesterol and Bile: CYP7A1, HMGCR, LDLR, SREBF1 Mitochondria and Inflammation: CAT, CRP, FOXO3, GPX1, IFNG, IL6, NRF2, SIRT3, SOD2, TNF, UCP1/2/3

All of the Lifecode Gx reports include

  • personalised, colour coded genotype results

  • gene function and SNP impact descriptions

  • clinically relevant SNPs

  • nutrient and other epigenetic impacts

  • links to research evidence